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Build Multi-Agent LLM Systems with Python: Tool Integration and Persistent Memory Guide

Learn to build a production-ready multi-agent LLM system in Python with tool integration, persistent memory, and inter-agent communication using LangChain.

Build Multi-Agent LLM Systems with Python: Tool Integration and Persistent Memory Guide

I’ve been thinking about how we can make large language models more useful for complex tasks. A single AI assistant is good, but what if we could have a team of them? Each specialist working together, remembering past conversations, and using tools like calculators or web search. That’s the promise of a multi-agent system.

Why did this topic grab my attention? Because building one of these systems is like assembling a team of brilliant colleagues. You’re not just asking one model to do everything. You’re creating a workflow where different models, each with a specific strength, collaborate. It’s more powerful, more flexible, and honestly, more fun to build.

Let’s start with the big picture. A multi-agent system has a few key parts. You need a way for agents to talk to each other, a shared memory so they don’t forget important details, and a set of tools they can use, like accessing an API or running a calculation. Think of it as building a small, intelligent company inside your computer.

Setting this up in Python is straightforward. You’ll need a few key libraries. First, we create a project structure and install our dependencies.

pip install langchain openai chromadb

Next, we need a place for agents to store and recall information. This is called persistent memory. We can use a vector database, which stores data in a way that helps the AI find relevant past conversations quickly. Here’s a simple way to set it up.

import chromadb
from langchain.vectorstores import Chroma
from langchain.embeddings import OpenAIEmbeddings

# Create a client and a collection for memory
client = chromadb.PersistentClient(path="./agent_memory")
embeddings = OpenAIEmbeddings()
vectorstore = Chroma(client=client, embedding_function=embeddings)

With memory ready, we can create our first agent. An agent is essentially a language model that can decide to use a tool. We’ll define a base class to handle common tasks. What makes an agent smart? It’s the ability to choose the right action from many possibilities.

from langchain.agents import AgentExecutor, create_openai_tools_agent
from langchain.prompts import ChatPromptTemplate

class BaseAgent:
    def __init__(self, name, tools, llm):
        self.name = name
        prompt = ChatPromptTemplate.from_messages([
            ("system", "You are a helpful assistant."),
            ("human", "{input}"),
        ])
        self.agent = create_openai_tools_agent(llm, tools, prompt)
        self.agent_executor = AgentExecutor(agent=self.agent, tools=tools)

Now, tools are what give agents their superpowers. A tool is a function the AI can call. For example, a tool to get the current weather. You define the function and describe it to the agent so it knows when to use it.

from langchain.tools import tool

@tool
def get_weather(city: str) -> str:
    """Fetches the current weather for a given city."""
    # Imagine this calls a real weather API
    return f"The weather in {city} is 72°F and sunny."

# Now, you give this tool to your agent's toolkit.

Here’s a question for you: what happens when one agent’s task depends on another’s output? This is where the orchestrator comes in. It’s the manager of the system. It listens for tasks, decides which agent is best for the job, and passes messages between them. It makes sure the research agent talks to the writing agent when the report is ready.

To make this work, we need communication. Agents can’t just shout into the void. We set up a simple message bus. When the research agent finishes, it posts its findings to a shared channel. The writing agent subscribes to that channel and gets to work.

import asyncio
from collections import defaultdict

class MessageBus:
    def __init__(self):
        self.channels = defaultdict(list)
    
    async def publish(self, channel, message):
        """Sends a message to a channel."""
        for callback in self.channels[channel]:
            await callback(message)
    
    def subscribe(self, channel, callback):
        """Listens for messages on a channel."""
        self.channels[channel].append(callback)

# An agent can subscribe to the 'research_findings' channel.

With the pieces in place, you can start defining specialized agents. A research agent might have tools for web search and data scraping. An analysis agent could have tools for statistics and charting. A writing agent focuses on structuring information into clear reports. They all share the same memory and message bus.

Testing is crucial. You start with simple tasks: “Research the history of coffee and write a summary.” Watch how the agents divide the work. Does the research agent store its findings in memory? Does the writer find them? You’ll quickly see where the conversation breaks down and can fix the prompts or the tool descriptions.

Remember, the goal is a smooth collaboration. The system should feel like a well-oiled machine. Each agent does its part without you needing to micromanage every step. It’s about creating a process, not just a single response.

As you build, you’ll run into challenges. Agents might get stuck in loops or use tools incorrectly. The key is clear instructions and good error handling. For instance, if a tool fails, the agent should have a way to try a different approach or ask for help.

What does it take to run this in a real application? You need to think about cost, speed, and reliability. Using cheaper, faster models for simple steps and reserving the powerful models for complex reasoning can save money. Caching frequent responses also helps.

I find the most rewarding part is watching the agents hand off tasks autonomously. You give the system a complex goal, and it just…figures it out. It plans, executes, and learns from the shared memory. That’s when you see the true potential.

Building this isn’t just about the code. It’s about designing a system where intelligence is distributed. Each agent is a cog in a larger machine, and getting them to work in harmony is the real achievement. It opens up possibilities for automation that feel genuinely clever.

I hope this guide helps you start your own project. Try building a simple two-agent system first. Have them talk to each other about a topic you love. You’ll learn more by doing than by reading any article.

If this exploration of multi-agent systems sparked ideas for you, let me know in the comments. What kind of AI team would you build? Share this with someone who loves to tinker with the future of AI. Let’s keep the conversation going

Keywords: multi-agent LLM system Python, LangChain agent framework tutorial, persistent memory vector database, tool integration LLM agents, inter-agent communication patterns, multi-agent architecture design, OpenAI GPT agent orchestrator, vector storage agent memory, custom tools API integration, production LLM agent deployment



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